GO Mapper

Developed by Marcel Smid

Introduction

GO Mapper is an application that uses the functional annotation of the Gene Ontology consortium to analyse gene expression data. The application loads microarray or SAGE derived data, links the genes to GO-terms and then uses the actual measured expression level to weigh the associated terms. The aggregate of the weighted GO-terms shapes the functional profile of the experiment. The weight of a term is calculated as an Expression Quotient (EQ); In short, the EQ is calculated as the quotient of the average expression ratio of the genes associated with a GO-term and the average expression ratio of all genes measured on the array.
The GO Mapper can be used for analysis of human, mouse, rat, zebrafish, fruitfly and yeast data.

For more information:

Publication
Bioinformatics April 19, 2004 20(16):2618-2625	M.Smid L.C.J. Dorssers	GO-Mapper: Functional analysis of gene expression data using the expression level as a score to evaluate Gene Ontology terms. Supplementary Information of this article: [Figure 5] [Figure 6] [Excel-file UV-response] [Excel-file Mouse development]

Downloads:

GO Mapper 1.01		2004
Manual	Pdf file
Executable	For Windows only. Updated April 26, 2004. ZIP archive, includes "GOMapper.exe", "ug2go.txt", "GOManual.pdf" and "disclaimer.txt".
Perl source code	These zip files contains my working version of the software as well as the script to update the ug2go.txt file. Note that both scripts are not tested on different OS-platforms. Please let me know of any bugs. I would like to receive modifications/improvements via e-mail. Time permitting, I will incorporate these into subsequent versions.
	GO Mapper Updated April 26, 2004.
	Ug2Go This is the current datafile, containing the Gene Ontology data and the gene to GO links. For those who already have the application but wish to use a newer datafile. Version stamp 7: Updated from GO: Fri Apr 02 23:15:13 PST 2004 Version and date from yeast data (SGD) version 1.858 (04/04/2004), Unigene build 166.
	UpdateGO Updated April 26, 2004.

GO MapperDeveloped by Marcel Smid

GO Mapper

Developed by Marcel Smid